Testimonials

The HTS Facility at Children’s Cancer Institute has used our Roylan Storage Pod system of a MultiPod controller together with SanFrancisco and Dundee enclosures since 2017. This system has fundamentally improved our daily handling of compound screening source plates by eliminating the problem of multiple freeze/thaw cycles and allowing us to reliably store low dead volume plates. The ability to “dry” plates under a DMSO rich atmosphere has also allowed us to retain plates for longer without the concern of moisture ingress. While our system is not that large it is incredibly straightforward to use for new and experienced users alike and has performed reliably for the entire time since installation. Stuart has been an ever present source of valuable advice and assistance both prior to purchase and in the years since.

Children’s Cancer Institute. UNSW Medicine, Australia

Trust lies at the heart of our work at Domainex — our clients depend on us to deliver reliable and accurate results, and we, in turn, rely on companies like Roylan to help us continue to make this a reality. For over seven years, The Roylan pod low-nitrogen and -humidity storage containers have played a central role in helping us to preserve the integrity of our fragment library and small molecules, whether internally generated or externally sourced. As many of our libraries are stored in hygroscopic solvents like DMSO, it is vital for us to have a reliable system, like the pods from Roylan, to prevent hydrolytic & oxidative degradation over time.

Additionally, our Roylan Pods allow us to avoid repeated freeze-thaw cycles, which are known to compromise the integrity of small molecules. By keeping the compounds in stable, room-temperature conditions, we eliminate the risks associated with these cycles, ensuring that our libraries remain at a high purity for longer periods. Their compact design enables us to significantly reduce our compound storage footprint. By minimizing the need for extensive freezer space, we can store our libraries efficiently without compromising their stability, freeing up valuable lab space. This reduction in freezer dependence is not only cost-effective but also environmentally conscious.

The synergy between our Roylan Pods, compound management system, and liquid automation ensures that the compounds we work with are in optimal condition for the work we perform, from resolving ligand-target complex structures to calculating binding kinetic parameters. For our clients, this means greater confidence in the reproducibility & accuracy of our services. Furthermore, by knowing that their compounds are preserved at the highest standards, our clients can trust that costs, both time and monetary, are minimised. Maintaining compound integrity directly impacts our success and the success of our clients’ programs. Roylan’s storage solutions are integral to achieving that.”

You can visit Domainex at https://www.domainex.co.uk

Domainex

Since 2015, the Alzheimer’s Research UK Oxford Drug Discovery Institute has relied on Roylan’s storage Pods for managing compounds across over 20 drug discovery projects. The Pods have proven to be an indispensable asset, offering superior organization, reliability, and ease of access to our compound libraries containing over 350,000 compounds. Their robust design ensures the integrity of our compounds, maintaining optimal storage conditions and minimising the risk of degradation. The user-friendly interface and efficient inventory management system have streamlined our workflows, giving us confidence in the integrity of our compounds and allowing us to focus on the science. Roylan’s Pods have consistently supported our rigorous demands for robust assay development, ensuring reproducibility of our data and contributing significantly to the success of our projects. We highly recommend Roylan’s storage solutions to any team looking for dependable, high-quality storage systems for their critical compound collections.

Oxford Drug Discovery Institute

As a small molecule drug discovery company, we value the stability and accessibility of our compound collections highly.

We have been using a StoragePod V2 Controller with Dundee StoragePods for two years now and couldn’t be happier. We find that they work equally well for short term storage of compounds to be assayed as well as long term storage of our high-throughput libraries.

The staff at Roylan Developments are both helpful and knowledgeable, responding quickly to technical questions and maintenance requests.

Previously we were storing our compounds at -20 ºC, which resulted in hydration of our stock solutions and became increasingly unwieldy as our collection grew. The ease at which we can store and access our compounds now is a breath of fresh air (or nitrogen!).

Samsara Therapeutics

We purchased our StoragePod unit back in 2018 for our DMSO based compound libraries. A very reliable and easy to use system that includes a V2 controller and the Dundee StoragePods. I must point out the excellent service provided by Stuart and the team, which manifest in a quick, pleasant, and professional response to every question and demand. When we had to replace the controller oxygen sensor, the whole procedure from identifying the problem, through shipping of the part to a video session for installation guidance took less than two days! Thank you, Roylan Developments.

Anima Biotech

We purchased our first StoragePod V2 Controller and the first Dundee pods year 2010 to host small molecule libraries in DMSO on ECHO (acoustic dispenser from BeckmanCoulter) compatible plates, as we started our High Throughput Biomedicine HTB core laboratory at Institute for Molecular Medicine Finland FIMM. Since then, we have acquired more compounds and thus more Pods, and currently we have 70 Dundee Pods and around 10 short Dundee Pods. On top, we have 6 Helsinki Pods, specially designed for us, as we wanted also to store undissolved compound vials in racks under nitrogen, not only plates.

The Pods are convenient, as they can be stored in different temperatures. We have some Pods in freezers and some at +4 degrees Celsius. Most of the frequently used compound stocks we store at room temperature. Our functional quality control testing shows, that almost all compound stocks in DSMO have remained active at room temperature, the dark low oxygen and low relative humidity environment has been sufficient.

Also, the Pods have helped us greatly in keeping our DSMO dry. Especially in the summertime compound plates with DMSO get wet, but we can “dry” them with some sacrificial DMSO in the Pods. This has prolonged the lifetime of the source plates significantly. We are able to keep the DMSO% close to 90% all times for years despite weekly or monthly use.

A few years ago, as an upgrade we purchased the automated MultiPod Controller and four San Francisco pods. The Controller is automatically taking care of the San Franciso Pod contents, and they are easy to access by the users to get their pre-drugged assay plates when they need them. The smaller Pods are still in use and can be easily flushed with the same Controller. This system is essential to our daily laboratory operations.

Institute for Molecular Medicine Finland

User-friendly and low maintenance cost makes the StoragePod system an invaluable asset in our daily laboratory work. The device enables easy access to compounds when needed and provides minimal DMSO moisture absorption in a nitrogen atmosphere. The compact size of StoragePod system is also a great advantage when it comes to laboratory space.

In our company the StoragePod system is mostly used to store DMSO-based compound libraries in Labcyte Echo-qualified plates both between experiments and long-term storage at -20 degrees. The system saves significant costs and the time required to re-make fresh microplates.

Drug discovery company based in Poland

We have been using the MultiPod system since December 2020 and have expanded the number of pods on several occasions. We have eleven pods that are in regular use as a core piece of our compound management strategy. The system has been very reliable for us, with no failures in the past three years of use. The addition of extra pods has been carried out during routine servicing and didn’t require any system down time. Stuart and the team have been great to work with since our system was installed.

MOA Technology

When searching for an efficient and cost-effective compound storage solution, Roylan Developments came recommended. It was a pleasure to work with Stuart Naylor and the Roylan team and we could not be happier with our new MultiPod Storage Controller and San Francisco StoragePod.

The system was extremely easy to install and to configure, taking less than 30 mins total, and accessing it takes little to no effort. Additionally, the scalability is unmatched, with one MultiPod Controller operating up to 20 StoragePods.

We plan to use this system to store various lyophilized compounds as well as compounds in DMSO, and we will be expanding upon the number of StoragePods soon!

USA-based Life Science Company

Our research facility focuses on high-throughput screening of compound library for drug discovery and repurposing to target cancers and microbial infections. The MultiPod system from Roylan offers a highly reliable solution for compound library storage. The MultiPod system has outstanding advantages in terms of capacity, minimal maintenance and easy set-up. The customer service provided by Roylan is direct and efficient. They offered immediate and courteous assistance to help us interpret the messages in the system and achieved a fast and timely delivery of a new replacement oxygen sensor.

The Hong Kong Polytechnic University

Drug-discovery efforts in our laboratory focus on screening and development of small-molecule inhibitors that target HIV and cancer. Our efforts are often early-stage and we have little knowledge of compound stability both in solution and as powders to light, humidity, or oxygen. Therefore, protection of these valuable compounds is vital to our research efforts so that we know we are using our compounds in their most pure and uncompromised forms.

We have been using the San Francisco StoragePod from Roylan for several years and it has become a vital part of our laboratory’s drug library storage. We bank all of our solutions and powders in an easily accessed and organized way, the system is extremely easy to maintain, and with the few issues that have arisen, we have received prompt and courteous service, even from “across the pond”.

University of Pittsburgh School of Medicine

We acquired our MultiPod system for storing our compound libraries from Roylan in 2016. As a core facility at an academic institution, the MultiPod storage system was a great fit in terms of capacity, reliability, and price point. We originally acquired two San Francisco StoragePods, three Short Dundee StoragePods, and a controller unit for storing our DMSO-based compound libraries in Echo-formatted plates at room temperature. We also have a MiniPod controller in case we need to move compounds off site and which can serve as a backup controller if our MultiPod controller needs off-site service. The system has worked well for our compound storage needs and is very low maintenance. We trust that the integrity of our compounds will be preserved while in the storage system. The system has flexible capacity, and we recently capitalized on that flexibility to accommodate our growing compound collection. We acquired a Dundee StoragePod for DMSO flushing and an additional San Francisco StoragePod; the order was painless and the delivery was lightning fast. For service, Roylan has always been prompt, efficient, and economical. When we had an issue with low humidity in our lab causing a line flush time out, Roylan came up with a solution and were able to get our system serviced quickly.

The Chemical Biology platform at NCMM